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American Society of Microbiology ABMM Sample Questions (Q101-Q106):

NEW QUESTION # 101
A patient develops a severe skin and soft tissue infection following a boating accident in the Gulf Coast.
Wound cultures grow a Gram-negative, halophilic bacterium that is oxidase-positive. The MOST likely organism is:

  • A. Pseudomonas aeruginosa
  • B. Shewanella putrefaciens
  • C. Aeromonas hydrophila
  • D. Vibrio vulnificus

Answer: D


NEW QUESTION # 102
A patient with a history of neutropenia following chemotherapy develops a severe pneumonia.
Bronchoalveolar lavage fluid reveals the presence of hyaline, septate hyphae with frequent dichotomous branching at acute angles. Culture yields a filamentous fungus that produces conidiophores with a vesicle bearing phialides that release chains of conidia. The MOST likely genus is:

  • A. Mucor
  • B. Aspergillus
  • C. Fusarium
  • D. Rhizopus

Answer: B


NEW QUESTION # 103
Which of the following bacterial genera inherently possesses D-alanyl-D-lactate peptide subunits in its peptidoglycan precursors, conferring natural, high-level resistance to vancomycin?

  • A. Enterococcus (e.g., E. gallinarum, E. casseliflavus carrying vanC)
  • B. Leuconostoc
  • C. Staphylococcus
  • D. Streptococcus

Answer: B


NEW QUESTION # 104
Under the Clinical Laboratory Improvement Amendments (CLIA), participation in an approved external Proficiency Testing (PT) program serves primarily to:

  • A. Determine the reference intervals (normal ranges) for quantitative assays performed by the laboratory.
  • B. Fulfill requirements for laboratory accreditation by The Joint Commission only.
  • C. Provide an objective, ongoing assessment of the accuracy and reliability of the laboratory's testing compared to its peers.
  • D. Validate the performance characteristics (e.g., sensitivity, specificity) of newly implemented test methods.

Answer: C


NEW QUESTION # 105
A research team is investigating the mechanism of bacterial resistance to a novel fluoroquinolone antibiotic.
They isolate a resistant strain of Escherichia coli from a patient with a urinary tract infection. Genetic analysis of this strain reveals a point mutation in the gyrA gene. This mutation MOST likely results in:

  • A. Modification of the ribosomal target site, preventing antibiotic binding.
  • B. Production of an enzyme that inactivates the fluoroquinolone molecule.
  • C. Alteration of the DNA gyrase enzyme, reducing its affinity for the fluoroquinolone.
  • D. Increased expression of efflux pumps that actively transport the antibiotic out of the cell.

Answer: C


NEW QUESTION # 106
......

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